Eastern Along Pharmaceutical Co., Ltd

Feature

• Cyclo-oxygenase inhibitory NSAIDs

• Potent, non-narcotic, nonsteroidal, analgesic agent with anti-inflammatory and antipyretic activity.

• Significantly more potent than pentazocine, meperidine, and codeine as an analgesic

• Four times as potent on a mg-per-mg basis as phenylbutazone

Advantage

1. Excellent anti-endotoxin effect

Endotoxin is a component of the cell wall of Gram-negative bacteria called lipopolysaccharide.

 2. Significant effect on antipyretic, analgesia and inflammatory

Reduce fever-prone animals’ body temperature of to normal without any effect on normothermia. More potent than compound amino Bilin, amenia, aspirin, codeine, and phenylbutazone. As phenylbutazone has a rapid effect , Alphalin can relieve pain within 15 minutes. Alphalin also has miraculous effect on various inflammatory pains.

3. Safety

Alphalin is not easy to produce anaphylaxis and irritation. No immunosuppression, no stress response, no addiction and other side effects. Alphalin is very suitable for the treatment of virus disease such as blue ear disease and pyrexia.

4. Significantly improve efficacy of the combined antibiotics

Combination with antibiotics can effectively treat animals various bacterial infections and concurrent pyrexia. Alphalin can improve efficacy, shorten treatment duration, and effectively reduce the side effects of antibiotics on animal organisms (with penicillins, cephalosporins, tetracyclines, tilmicosin, florfenicol and other antibiotics).

Indications

1. Swine:

• For the treatment of pyrexia such as unknown fever, influenza, postpartum inflammation and high body temperature caused by endotoxin.

• For analgesia and anti-stress on the wounds, joints, and muscle pain caused by disease No. 5, streptococcus, parasitism, enteritis, etc.

• For treatment of inflammation caused by various types of diseases. When combine with most of the antibiotics can improve the efficacy of antibiotics.

• Maintain the stability of blood pressure and vascular osmotic pressure, relieving pleural effusion and cellulosic exudation caused by Haemophilus accessory Haemophilus, infectious pleuropneumonia and so on.

2. Dairy Cows:

• For the control of pyrexia associated with bovine respiratory disease, endotoxemia and acute bovine mastitis.

• For the control of inflammation in endotoxemia.

Antipyretic and Analgesic Effects

Table 1 Comparison of analgesic effects of several drugs on mice torsion caused by acetic acid

Table 2 Comparison of antipyretic effects of several drugs on pyrexia induced by peptone in rabbits (7h)

Usage and dosage

1. Swine

The recommended dose for control of pyrexia, control of inflammation in endotoxemia is 1.1 to 2.2 mg/kg of body weight given by slow intravenous administration either once a day as a single dose intervals for up to 3 days.

The recommended dose for the prevention of postpartum lactation disorder syndrome is 8-10ml / head of sow given by intravenous administration after delivery.

The recommended dose for the reduction of incidence of diarrhea and increase the survival rate is 0.3ml/head of piglet given by single dose intravenous administration when weaning.

2. Ruminants

The recommended dose for control of pyrexia associated with bovine respiratory disease and endotoxemia and control of inflammation in endotoxemia is 1.1 to 2.2 mg/kg (22mL/100 kg) of body weight given by slow intravenous administration either once a day as a single dose or divided into two doses administered at 12-hour intervals for up to 3 days. The total daily dose should not exceed 2.2 mg/kg of body weight. Avoid rapid intravenous administration of the drug. The recommended dose for acute bovine mastitis is 2.2 mg/kg of body weight given once by intravenous administration.

Adverse Reactions

Intramuscular injection can stimulate the local area. Long-term high dose use of this product may damage animal gastric ulcer and kidney function.

Precautions

1. Animals with peptic ulcer should be used with caution.

2. Concomitant use of r non-steroidal anti-inflammatory drugs should be avoided..

Withdrawal Period

Cattle and swine, 28 days.

Specification

Each 100ml contains 5g C14H11F3N2O.

Package

100ml/bottle

Storage

Shading, sealed preservation.